Figure 4.

BCAA restriction has little impact on hepatic metabolites in Zucker-fatty rats. Hepatic metabolites were measured in male ZFR or ZLR fed the LF or LF-Res diets. (A–E) Hepatic organic acid levels; (F–I) Hepatic short chain acylcarnitine levels; (J) Hepatic medium-long chain acylcarnitines. (K–L) Hepatic fatty acyl CoA's. n = 9–15 per group. Data represent mean ± SEM. Statistical differences indicated by: *: P < 0.05, **: P < 0.01, ***: P < 0.001 comparisons indicated by the connecting lines or in the absence of connecting lines vs LF-ZLR, and ###: P < 0.001 vs LF-ZFR.