Figure S15.

Glucose tolerance in [PPG-rtTA; TRE-Nkx6.1] mice. Before and after doxycycline diet, [PPG-rtTA; TRE-Nkx6.1] mice and the PPG-rtTA controls (A–C), or ATTAC-challenged [PPG-rtTA; TRE-Nkx6.1; PANIC-ATTAC] mice and the [PPG-rtTA; PANIC-ATTAC] controls (D–F), were subjected to oral glucose tolerance test and assayed for blood glucose. n ≥ 7 mice per condition. (A and D) Blood glucose concentrations at the indicated time points are presented as mean ± SEM. *P < 0.05, **P < 0.01 versus the TRE-Nkx6.1 negative controls, by unpaired t-test. (B, C, E and F) Areas under curve of individual mice before and after doxycycline are presented as dots and connected by line.