Figure 11.

New proposed methodology to accelerate progress in medicine and science: Schematic to situate the proposed dynamic outcome measures in the network of knowledge for Precision Psychiatry. (A) Higher layers of outcome data drive basic science and patient care at the bottom layers, but the “evidence-based” outcome of current behavioral analyses prevents personalized medical practices, possibly misinforming bottom layers and negatively impacting decision-making in basic research and patient care. (B) The proposed statistical platform to transform current practices into personalized behavioral analyses targeting specific levels of precision involving signatures of motor-sensory based noise with higher likelihood of connecting with genetic factors by exhaustively characterizing different statistical classes of synaptic noise. The layer of behavioral analyses is targeted.