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. 2016 May 14;5(7):480–490. doi: 10.1016/j.molmet.2016.05.005

Figure 1.

Figure 1

Lipodystrophy in IRFKO mice. (A) Insulin receptor (IR) mRNA level of 6-wk-old WT control and IRFKO mice in BAT, iWAT, liver, hypothalamus, heart, BAT SVF, and iWAT SVF (n = 4–5). (B) Body weights of 6- or 12-wk-old male or female WT or KO mice (n = 6–9). (C) Gross morphology of gWAT (arrow). gWAT (D) or iWAT(E) weights and representative images of 6- or 12-wk-old WT or IRFKO mice (n = 6–9). (F) Lean and fat mass of 12-wk-old male or female WT or IRFKO mice measured by DEXA (n = 7–9). All qPCR data are normalized to TBP and all quantitative data presented as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.