Table 1. Macroscopic and histological evaluation of articular cartilage of the femoral condyle and tibial plateau at 20 weeks after surgery.

Score Group	Macroscopic score	Osteoarthritis score (OARSI score)
ACLT + OVX (n = 8)	2.5 (1.4, 2.7)*	15.2 (7.6, 18.2)*
ACLT + OVX + 3U calcitonin (n = 6)	1.2 (0.4, 1.3)*†	5.6 (3.7, 7.2)*†
ACLT + OVX + 15U calcitonin (n = 7)	0.9 (0.5, 1.1)*†	4.4 (2.8, 6.1)*†
Naïve (n = 8)	0.5 (0.2, 0.6)	1.8 (1.2, 2.8)
Calcitonin 15U (n = 6)	0.6 (0.1, 0.4)	2.2 (1.5, 3.2)

Values are given as the mean ± SEM. The groups received surgeries and treatments as described in the Methods; OARSI score: Osteoarthritis Research Society International (OARSI) grading system. *P < 0.05 vs the naïve group; ^†P < 0.05 vs the ACLT + OVX groups.