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. 2016 Jun 27;6:28684. doi: 10.1038/srep28684

Table 1. Altered gene expression in Δndk compared to PAO1.

Gene locus Name Gene function log2 ratio (Δndk/WT) P vaule
T3SS
 PA1690 pscU translocation protein in type III secretion 3.02 1.05E-20
 PA1691 pscT translocation protein in type III secretion 4.84 1.06E-23
 PA1692 PA1692 translocation protein in type III secretion 4.37 1.11E-26
 PA1693 pscR type III secretion system protein 1.23 1.30E-18
 PA1694 pscQ type III secretion system protein 6.87 6.27E-106
 PA1695 pscP translocation protein in type III secretion 17.11 2.30E-204
 PA1696 pscO translocation protein in type III secretion 16.91 3.66E-77
 PA1697 PA1697 type III secretion system ATPase 8.15 0
 PA1698 popN type III secretion outer membrane protein PopN 4.80 8.74E-160
 PA1699 pcr1 hypothetical protein 17.30 5.92E-59
 PA1700 pcr2 hypothetical protein 7.06 3.27E-41
 PA1701 pcr3 hypothetical protein 16.28 2.10E-38
 PA1702 pcr4 hypothetical protein 4.21 5.90E-19
 PA1703 pcrD type III secretory apparatus protein PcrD 2.02 9.36E-80
 PA1704 pcrR transcriptional regulator PcrR 1.91 3.68E-06
 PA1705 pcrG type III secretion regulator 5.24 1.90E-83
 PA1706 pcrV type III secretion protein PcrV 5.64 0
 PA1707 pcrH regulatory protein PcrH 6.31 1.94E-209
 PA1708 popB translocator protein PopB 5.50 0
 PA1709 popD translocator outer membrane protein PopD 5.99 0
 PA1710 exsC exoenzyme S synthesis protein C 4.05 0
 PA1711 exsE hypothetical protein 4.12 5.97E-235
 PA1712 exsB exoenzyme S synthesis protein B 4.42 2.33E-175
 PA1713 exsA transcriptional regulator ExsA 4.06 4.80E-157
 PA1714 exsD hypothetical protein 4.78 0
 PA1715 pscB type III export apparatus protein 5.84 2.10E-115
 PA1716 pscC type III secretion outer membrane protein PscC 3.51 4.36E-184
 PA1717 pscD type III export protein PscD 6.02 7.01E-76
 PA1718 pscE type III export protein PscE 5.21 3.45E-31
 PA1719 pscF type III export protein PscF 3.92 7.80E-50
 PA1720 pscG type III export protein PscG 4.01 3.03E-46
 PA1721 pscH type III export protein PscH 3.95 2.41E-33
 PA1722 pscI type III export protein PscI 4.28 3.92E-39
 PA1723 pscJ type III export protein PscJ 3.06 2.39E-47
 PA1724 pscK type III export protein PscK 3.94 9.94E-12
 PA1725 pscL type III secretion system protein 2.49 2.20E-16
 PA3841 exoS exoenzyme S 3.69 0
 PA0044 exoT exoenzyme T 4.54 0
 PA2191 exoY adenylate cyclase 2.97 2.05E-46
 PA3842 spcS chaperone 3.69 1.27E-68
QS signal molecule synthetase and regulator
 PA1432 lasI autoinducer synthesis protein LasI −3.12 0
 PA3476 rhlI autoinducer synthesis protein RhlI −2.09 0
 PA0996 pqsA coenzyme A ligase −5.81 0
 PA0997 pqsB alkyl quinolones biosynthesis protein −6.96 0
 PA0998 pqsC alkyl quinolones biosynthesis protein −5.91 4.61E-260
 PA0999 pqsD 3-oxoacyl-synthase III −4.22 0
 PA1000 pqsE Quinolone signal response protein −4.12 8.01E-254
 PA2587 pqsH FAD-dependent monooxygenase −4.45 0
 PA1430 lasR transcriptional regulator LasR −1.03 1.42E-240
 PA3477 rhlR transcriptional regulator RhlR −3.39 0
 PA1003 mvfR transcriptional regulator MvfR (PqsR) −1.31 6.81E-64
 PA1898 qscR quorum-sensing control repressor 3.32 7.68E-65
Virulence associated exoproducts
 PA3724 lasB elastase LasB −6.76 0
 PA1871 lasA LasA protease −7.03 0
 PA1246 aprD alkaline protease secretion protein AprD −2.92 2.19E-116
 PA1247 aprE alkaline protease secretion protein AprE −2.95 5.20E-102
 PA1248 aprF alkaline protease secretion outer membrane protein AprF −2.50 3.21E-55
 PA1249 aprA alkaline metalloproteinase −1.25 0
 PA0026 plcB phospholipase C −2.43 1.02E-219
 PA4210 phzA1 phenazine biosynthesis protein −0.98 0.051979
 PA4211 phzB1 phenazine biosynthesis protein −2.21 1.12E-53
 PA4212 phzC1 phenazine biosynthesis protein PhzC −1.81 3.68E-06
 PA4214 phzE1 phenazine biosynthesis protein PhzE; −2.42 4.68E-08
 PA4217 phzS flavin-containing monooxygenase −2.05 8.77E-114
 PA1899 phzA2 phenazine biosynthesis protein −3.04 1.79E-22
 PA1900 phzB2 phenazine biosynthesis protein −4.89 0
 PA1901 phzC2 phenazine biosynthesis protein PhzC −4.26 1.81E-58
 PA1130 rhlC rhamnosyltransferase −3.18 0
 PA3478 rhlB rhamnosyltransferase subunit B −7.00 0
 PA3479 rhlA rhamnosyltransferase subunit A −6.69 0
 PA2570 lecA PA-I galactophilic lectin −5.82 0