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. 2016 Jun 27;6:28599. doi: 10.1038/srep28599

Figure 4. BDNF delivery by FUS-enhanced intranasal drug delivery (IN + FUS) and FUS combined with IV drug injection (IV + FUS).

Figure 4

(a,b) are the immunohistochemistry staining of the whole brain horizontal section from mice in the IN + FUS and IV + FUS groups, respectively. FUS was targeted at the left caudate putamen. Locally enhanced delivery was achieved for BDNF administered either through IN or IV.