Table 3.
Use of IHC in the diagnosis of lymphomas
| Neoplasms | CD5 | CD10 | CD23 | CD43 | CD103 | Cyclin D1 | sIg, CIg |
|---|---|---|---|---|---|---|---|
| B-CLL/SLL | + | − | + | + | − | − | +; -/+ |
| Lymphoplasmacytic lymphoma | − | − | − | +/- | − | − | |
| Splenic marginal zone lymphoma | − | − | − | − | + | − | +; -/+ |
| Hairy cell leukemia | − | − | − | + | + + | +/- | +;- |
| Follicular lymphoma | − | +/- | −/+ | − | − | − | +;- |
| Mantle cell lymphoma | + | − | − | + | − | + | +;- |
| MALT lymphoma | − | − | −/+ | −/+ | − | − | +; +/- |
| Diffuse large B-cell lymphoma | − | −/+ | NA | −/+ | NA | − | +/-; -/+ |
| Burkitts lymphoma | − | + | − | − | NA | − | +; - |
+, positive; +/-, >50% positive; -/+, <50% positive; -, < negative; CIg, intracytoplasmic immunoglobulin; sIg, surface immunoglobulin.