TABLE 1.
Comparison of Xpert HPV test results using paired vaginal and cervical specimens
| Virus and vaginal specimen type | No. of cervical specimens |
PPA (%) (95% CI), NPA (%) (95% CI), OPA (%) (95% CI), kappa value (95% CI) | ||
|---|---|---|---|---|
| Positive | Negative | Total | ||
| HPV-16 | 94.3 (92.8, 95.8), 99.6 (99.2, 100.0), 99.4 (98.9, 99.9), 0.91 (0.86, 0.97) | |||
| Positive | 33 | 4 | 37 | |
| Negative | 2 | 966 | 968 | |
| Total | 35 | 970 | 1,005 | |
| HPV-18/45 | 81.3 (78.8, 83.8), 98.8 (98.1, 99.5), 98.5 (97.7, 99.3), 0.63 (0.48, 0.77) | |||
| Positive | 13 | 12 | 25 | |
| Negative | 3 | 977 | 980 | |
| Total | 16 | 989 | 1,005 | |
| Other hrHPVs | 91.1 (89.3, 92.9), 94.8 (93.4, 96.2), 94.4 (92.9, 95.9), 0.72 (0.65, 0.79) | |||
| Positive | 82 | 48 | 130 | |
| Negative | 8 | 867 | 875 | |
| Total | 90 | 915 | 1,005 | |
| All hrHPVs | 90.3 (88.4, 92.2), 93.9 (92.4, 95.4), 93.4 (91.8, 95.0), 0.74 (0.70, 0.79) | |||
| Positive | 112 | 54 | 166 | |
| Negative | 12 | 827 | 839 | |
| Total | 124 | 881 | 1,005 | |