TABLE 4.

Summary of Xpert Carba-R performance for different carbapenemase targets versus that of the reference method (culture plus sequencing) for combined clinical and contrived specimens

Target gene	Sensitivity (% [95% CI])	Specificity (% [95% CI])	PPV (%)	NPV (%)
IMP-1	96.3 (81.0–99.9)	100 (99.4–100)	100	99.8
VIM	93.5 (78.6–99.2)	99.8 (99.1–100)	96.7	99.7
NDM	100 (86.8–100)	99.8 (99.1–100)	96.3	100
KPC	96.7 (82.8–99.9)	99.3 (98.3–99.8)	87.9	99.8
OXA-48	95.0 (83.1–99.4)	99.8 (99.1–100)	97.4	99.7