TABLE 1.
Clinical characteristics of patients included in the study preimplementation and postimplementation of microarray-based identification of Gram-negative organisms from blood culture broths using BC-GN
| Characteristica | Pre-BC-GN | Post-BC-GN | P valueb |
|---|---|---|---|
| No. | 98 | 97 | NA |
| Mean age (SD), yr | 60.0 (14.7) | 60.3 (15.2) | 1.00 |
| Age range, yr | 22–93 | 20–92 | NA |
| Male (%) | 63 (64.3) | 57 (58.8) | 0.46 |
| ANC < 500, no. (%) | 15 (15.3) | 12 (12.4) | 0.68 |
| Admission to ICU, no. (%) | 42 (42.9) | 38 (39.2) | 0.66 |
| Mean APACHE II score, ICU patients (SD) | 20.4 (8.0) | 18.0 (6.9) | 0.24 |
| Infectious diseases specialist consulted, no. (%) | 38 (38.8) | 40 (41.2) | 0.77 |
| Immunosuppressive therapy, no. (%) | 50 (51.0) | 40 (41.2) | 0.20 |
| Penicillin allergy, no. (%) | 10 (10.2) | 11 (11.3) | 0.82 |
| Comorbidity, no. (%) | |||
| Cardiovascular disorder | 29 (29.6) | 21 (21.6) | 0.25 |
| Chronic lung disease | 3 (3.1) | 4 (4.1) | 0.72 |
| Liver disease | 15 (15.3) | 9 (9.3) | 0.28 |
| Solid organ tumor | 37 (37.8) | 36 (37.1) | 1.00 |
| Lymphoproliferative disorder | 16 (16.3) | 20 (20.6) | 0.47 |
| Diabetes | 34 (34.7) | 25 (25.8) | 0.21 |
| Hypertension | 55 (56.1) | 44 (45.4) | 0.15 |
| Genitourinary disease | 41 (41.8) | 36 (37.1) | 0.56 |
| Connective tissue disorder | 6 (6.1) | 4 (4.1) | 0.75 |
| CNS disease | 5 (5.1) | 7 (7.2) | 0.57 |
| Intraabdominal process | 28 (28.6) | 26 (26.8) | 0.87 |
| History of organ transplant | 14 (14.3) | 15 (15.5) | 0.84 |
| Source of bacteremia, no (%) | |||
| Genitourinary | 38 (38.8) | 34 (35.1) | 0.66 |
| Intraabdominal | 32 (32.7) | 32 (33.0) | 1.00 |
| Intravascular line | 15 (15.3) | 14 (14.4) | 1.00 |
| Indwelling device | 1 (1.0) | 1 (1.0) | 1.00 |
| Respiratory | 5 (5.1) | 4 (4.1) | 1.00 |
| Wound | 2 (2.0) | 1 (1.0) | 1.00 |
| Unknown | 5 (5.1) | 11 (11.3) | 0.13 |
a
ANC, absolute neutrophil count; CNS, central nervous system.
b
All P values were determined by the Fisher exact test, except for mean age, which was analyzed by the Student's unpaired t test, and the APACHE II score, which was analyzed by the Mann Whitney U test. NA, not applicable.