1 |
Spanish samples from 2 time points, seronegative (titer < 64) to seropositive (titer ≥ 64) |
40 patients (80) |
2 |
Spanish samples from 2 time points, seropositive (titer ≥ 64) to seropositive (≥2-fold increase in titer) |
41 patients (82) |
3 |
Spanish samples from 2 time points, seropositive (titer ≥ 64) to seropositive (but <2-fold increase in titer) |
18 patients (36) |
4 |
Spanish samples from 2 time points, seronegative (titer = 0) to seronegative (titer = 0) |
5 patients (10) |
5 |
Samples from healthy Spanish blood donors |
23 donors (23) |
6 |
Spanish samples from a single time point, confirmation of tularemia by bacterial culture |
5 patients (5) |
7 |
Samples from healthy adult controls from Orange County, CA (an area of nonendemicity), with no known history of tularemia |
12 donors (12) |