Fig. 1.

Median time female mosquitoes spent in contact with kinin analogs 1728 and 1729 (at 1-mM and 600-µM concentrations in sucrose solution) or with a 10% sucrose solution (S) as control. Females were videorecorded for 1 h (Movies S1 and S2). Each dot represents the duration of a single encounter of a female with the diet, and the median time spent in contact is indicated by a red line. Three independent replicates were performed, for a total of 60 females (20♀ × 3) exposed per treatment. The total number of encounters (En) is shown below each column; some females made multiple encounters. The maximal recorded time of an individual encounter was 10 min. Data were analyzed by Kruskal–Wallis nonparametric ANOVA followed by Dunn’s multiple comparisons test. Black lines above the figure define the contrasts in pairs of medians. Asterisks denote significant differences (*P < 0.05, ***P < 0.001, ****P < 0.0001); ns, not significant.