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. 2016 Feb 23;9(1):e3467. doi: 10.17795/ijcp-3467

Appendix A3. Quality of Studies Assessing the Association Between XRCC1 Arg194Trp Polymorphism and Breast Cancer a,b.

Study (year) Source of Control Population Ethnicity Sample Size Menopausal Status HWE Reported
Duell (2001) + + + A +
Kim (2002) + - + + +
Han (2003) + B + C +
Smith (2003) + + + - +
Smith (2003) + + + - +
Moullan (2003) + - + - +
Forsti (2004) + - + - +
Deligezer (2004) - - + - +
Chacko (2005) + - + + +
Shen (2005) + A + + +
Patel (2005) + BD + + +
Pachkowski (2006) + + + - +
Thyagarajan (2006) + - + - +
Brewster (2006) + + + C +
Zhang (2006) + + + + +
Silva (2007) + + + + +
Smith (2008) + + + - +
Sangrajrang (2008) + - + + +
Mitra (2008) E + + D +
Loizidou (2008) E + + - +
Sobczuk (2009) - - + + +
Zipprich (2010) + D + C +
Ming-Shiean (2010) + - + - +
Sterpone (2010) E + + - +
Liu (2011) + + + - +
Przybylowska-Sygut (2013) + - + - +
Al Mutairi (2013) + D + - +
Ding (2014) + + + - +
McCullough (2014) + B + + +
Ramadan (2014) + - + A +
Smolarz (2014) + - + - +
Macias-Gomez (2015) - - + - +

a Definitions:Year, year of publication; positive sign (+), mentioned in the articles; negative sign (-), not mentioned in the article; Source of control means clinic (or hospital) based or population based; Population ethnicity means Caucasian, African-American and other ethnicity; sample size means calculable sample size; Menopausal status means adjustment of menopausal status (post, pre or both) for final measure of association using methods such as adjustment inregression models, restriction, stratification etc; HWE (Hardy Weinberg equilibrium) means calculated or reported HWE equilibrium.

b A, Calculated OR for different strata, but data not shown; B, Only mentioned to ethnicity without adjustment; C, Adjusted, but no detail presented; D, Matched controls, but no detail presented; E, Source of controls: volunteers.