Appendix A4. Quality of Studies Assessing the Association Between Arg280His Polymorphism and Breast Cancer a,b.
Study (year) | Source of Control | Population Ethnicity | Sample Size | Menopausal Status | HWE Reported |
---|---|---|---|---|---|
Moullan (2003) | + | - | + | - | + |
Chacko (2005) | + | - | + | + | + |
Metsola (2005) | + | + | + | A | + |
Pachkowski (2006) | + | + | + | - | + |
Zhang (2006) | + | + | + | + | + |
Smith (2008) | + | + | + | - | + |
Loizidou (2008) | B | + | + | - | + |
Sangrajrang (2008) | + | - | + | + | + |
Zipprich (2010) | + | C | + | D | + |
Liu (2011) | + | + | + | - | + |
a Definitions: Year, year of publication; Source of control means clinic (or hospital) based or population based; Population ethnicity means Caucasian, African-American and other ethnicity; Sample size means calculable sample size; Menopausal status means adjustment of menopausal status (post, pre or both) for final measure of association using methods such as adjustment in regression models, restriction, stratification etc; HWE (Hardy Weinberg equilibrium) means calculated or reported HWE equilibrium.
b A, Calculated OR for different strata, but data not shown; B, Source of controls: volunteers; C, Matched controls, but no detail presented; D, Adjusted, but no detail presented.