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Virulence of ΔmrsA in a murine model of invasive pulmonary aspergillosis. (A) Survival curve of mice that infected with wild type, ΔmrsA, ΔmrsAC and PBS. (B) Histopathological analyses were conducted using lung tissue isolated from the mice that sacrificed at the same day post infection with each strains. Periodic Acid–Schiff (PAS) stains was utilized to visualize fungal growth.
