Table II.
Demographic characteristics and plasma levels of lipids and inflammatory markers in patients with different stage of coronary stenosis.
| Variable | CAD(0) | CAD(1) | CAD(2) | CAD(3) | P-value |
|---|---|---|---|---|---|
| N | 43 | 14 | 20 | 16 | |
| Age, y | 60.43±12.44 | 61.00±14.01 | 60.44±10.76 | 62.75±8.86 | 0.909 |
| BMI, kg/m2 | 26.32±3.27 | 25.44±3.13 | 27.82±5.28 | 27.69±2.25 | 0.109 |
| W/H ratio | 0.91±0.10 | 0.95±0.10 | 0.96±0.09 | 0.96±0.07 | 0.234 |
| TC, mmol/L | 4.89±0.72 | 4.60±0.72 | 5.02±2.06 | 5.48±2.36 | 0.711 |
| TG, mmol/L* | 1.41 (1.22–1.63) | 1.25 (0.92–1.69) | 1.59 (1.19–2.12) | 1.88 (1.32–2.67) | 0.289 |
| HDL-C, mmol/L | 1.24±0.32 | 1.21±0.27 | 1.05±0.40 | 1.01±0.33 | 0.162 |
| LDL-C, mmol/L | 2.94±0.93 | 2.80±0.58 | 3.20±1.52 | 3.56±1.90 | 0.545 |
| hsCRP, mg/L* | 2.71 (1.81–4.05) | 2.34 (0.81–6.74) | 9.55 (4.25–21.45)a,b *** | 7.01 (2.96–16.66)a, ** | <0.001 |
| PTX3 * | 3.96 (3.13–5.01) | 4.71(1.86–11.90) | 7.62 (3.73–15.56)a, ** | 7.83 (4.04–15,16)a, * | 0.001 |
1
Continuous variables were compared by ANOVA and categorical variables by Chi-square test.
2
TG, hsCRP and PTX3 concentrations were presented as geometrical mean and 95% confidence interval (CI) for mean.
***
P<0.001;
**
P<0.01;
*
P<0.05 (Tukey’s post hoc test).
a
Significantly different from CAD(0) by Tukey’s post hoc test.
b
Significantly different from CAD(1) by Tukey’s post hoc test.
(BMI – body mass index; HT – hypertension; W/H – waist-to-hip ratio; TC – total cholesterol; TG – triglycerides; HDL-C – HDL-cholesterol; LDL-C – LDL-cholesterol; hsCRP – high-sensitivity C-reactive protein; PTX3 – pentraxin-3)