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. 2016 May 11;12(6):936–948. doi: 10.1080/15548627.2016.1162359

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licensee http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 5. — Enhanced OXPHOS drives differentiation of K562. (A to H) cellular profile was analyzed in K562 by flow cytometry for expression of TFRC (A, C, E, G and H) and GYPA (B, D and F) following 5 d culture in galactose (A and B), 5 d treatment with 2 µM and 4 µM oxamate (C and D), ATG7 knockdown alone (E and F) or +/− 10 nM NAC treatment (G) or 72 h 10 µM HCQ treatment +/− 10 nM NAC (H). Three independent experiments were performed in duplicate. (I and J) TFRC (I) and GYPA (J) levels were measured in CP CML CD34⁺ cells (n = 3) following 72 h 10 µM HCQ treatment. **, P ≤ 0.01; ***, P ≤ 0.001.