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. 2016 Mar 2;115(5):2536–2555. doi: 10.1152/jn.00902.2015

Table 2.

Electrophysiological properties of NaV currents in vestibular ganglion neurons

Inactivation
Activation
Time Course
Current/VGN Subpopulation V1/2, mV s, mV V1/2, mV s, mV G density, nS/pF tpeak, 0 mV, ms tpeak, −15 mV, ms τinact, 0 mV, ms
NaV (total)
    VGNs with INaI −76.9 ± 1.5 (13) 7.5 ± 0.4 (13) −40.1 ± 2.0 (6) 6.0 ± 0.6 (6) 8.4 ± 0.9 (6) 0.33 ± 0.03 (8) 0.42 ± 0.03 (10) 0.26 ± 0.02 (10)
    VGNs without INaI or INaR −79.5 ± 1.3 (3) 6.6 ± 0.2 (3) −38.6 (1) 6.2 (1) 7.24 (1) 0.25 ± 0.003 (3) 0.31 ± 0.01 (5) 0.21 ± 0.01 (4)
    cultured VGNs −76.3 ± 0.2 (12) 7.6 ± 0.1 (12) −36.5 ± 1.6 (11) 5.7 ± 0.4 (11) 8.7 ± 1.0 (11) 0.36 ± 0.01 (8) 0.45 ± 0.01 (8) 0.28 ± 0.01 (8)
NaS
    VGNs with INaI −74.6 ± 1.5 (13) 7.0 ± 0.3 (13) −39.8 ± 2.5 (6) 5.7 ± 0.8 (6) 6.1 ± 0.4 (6) 0.32 ± 0.03 (7) 0.40 ± 0.04 (8) 0.25 ± 0.02 (7)
    VGNs with INaR −65.8 ± 1.6 (8) 10.5 ± 0.3 (8) −32.3 ± 0.7 (6) 5.9 ± 0.5 (6) 3.1 ± 0.34 (5) 0.45 ± 0.04 (5) 0.57 ± 0.03 (5) 0.312 ± 0.01 (5)
NaI
    VGNs with INaI + INaS −102.1 ± 1.3 (23) 9.9 ± 0.6 (23) −47.5 ± 1.6 (9) 8.2 ± 0.4 (9) 1.0 ± 0.2 (9) 0.47 ± 0.03 (9) 0.53 ± 0.03 (11) 0.27 ± 0.03 (8)
NaR
    VGNs with INaR + INaS −31.4 ± 0.6 (23) 5.2 ± 0.2 (23) −16.5 ± 0.6 (8) 4.5 ± 0.2 (8) 1.5 ± 0.3 (7) 1.4 ± 0.1 (6) 3.1 ± 0.2 (6) 2.4 ± 0.1 (11)

Values are means ± SE (n). Sample sizes were smaller for activation parameters because higher recording quality is required. Room temperature, Cs+ internal, and Cs+ external solutions (Table 1). VGN, vestibular ganglion neurons; see text for additional definitions.