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. 2016 Apr 27;152(1):194–204. doi: 10.1093/toxsci/kfw081

FIG. 4.

FIG. 4

Copper exposure activates pro-inflammatory responses in BV2 cells when stimulated with fAβ. Conditioned media were collected and quantitatively analyzed for selected pro- and anti-inflammatory cytokines released from BV2 cells after 1-h fAβ (0.5 µM) stimulation. A, BV2 cells pre-exposed to 0.5 µM copper for 3 h or B, BV2 cells pre-exposed to 0.5 µM copper for 24 h. Each graph represents mean ± S.E.M. of 3 separate experiments in triplicates (n = 9). *P < 0.05 compared to the fAβ-stimulated group without pre-exposure to copper (open bar).