Fig. 5.

Mapping and alignment of retinotopically defined areas. A: individual frames from the cycle-averaged response to the topographic noise stimulus, showing that the moving stimulus evokes corresponding moving bands of neural activity in multiple cortical areas. See Supplemental Movie S3 for full movie. Inset shows positioning of cranial window. B: reliability of maps from short subsets of data, measured by correlation with map obtained from full 5 min of data. C and D: phase maps from 1 session in 1 mouse, demonstrating retinotopy in azimuth (C) and elevation (D). Color represents spatial position in degrees, based on phase of the Fourier response and the position and size of the monitor. Brightness represents Fourier amplitude. E: time course for an individual pixel in C before (green) and after (blue) deconvolution. F and G: average retinotopic maps (azimuth and elevation, respectively), resulting from alignment across subjects and sessions, with correspondence to known extrastriate areas based on demarcation in I. H: overlay of visual field-sign boundaries (black) with watershed transform of retinotopic location (gray) delineates known retinotopic regions. I: color-coded map shows patches of consistent gradient and sign, representing discrete retinotopic regions. Assignment of cortical area identity in H and I and wireframe boundaries in I is based on previous anatomical and imaging studies. Putative assignment to processing streams, based on Wang et al. (2012), is shown in blue (ventral) and magenta (dorsal). F–I: averaged across 15 sessions in 5 mice. Scale bars (for all panels), 500 μm. RL, rostrolateral area; AL, anterolateral area; LM, lateromedial area; P, posterior area; AM, anteromedial area; PM, posteromedial area; V1, primary visual cortex.