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Head-fixed visual discrimination task. A: schematic of head-fixed behavior paradigm, where the mouse must run on the ball, left or right, depending on orientation of the stimulus. B: distribution of response times from 15 sessions in 5 mice. C: performance as a function of response time for sessions in B, showing high performance during an optimal response window. D: median response time and percent correct through session duration, showing drop in performance toward the end of session.
