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. 2016 Jun 27;14(6):e1002491. doi: 10.1371/journal.pbio.1002491

Fig 8. Inhibiting β4 Integrin decreases fission.

Fig 8

Organoids grown in control media (ENR-Y; A) or in the presence of a β4 Integrin blocking antibody (B) were recorded by time-lapse imaging. The number of branches were measured every 6 h (C, S9 Data). Branch number increases more slowly in organoids grown in the presence of the β4 Integrin antibody (p < 0.05 from 78 h, t test; n = 21 from three replicates for both conditions), indicating a lower incidence of fission. The different background in panels A and B arises from phase contrast effects at different positions in a well relative to its centre that affect background intensity. Underlying data for panel C can be found in S9 Data.