Skip to main content
. Author manuscript; available in PMC: 2016 Jun 27.
Published in final edited form as: Transl Res. 2015 Sep 18;166(6):554–567. doi: 10.1016/j.trsl.2015.09.004

Figure 5. Bleomycin (BLM)-induced MMP-2 activity and AKT phosphorylation are inhibited in the lungs of aged male C57BL/6 mice by infusion of young adipose derived mesenchymal stem cells (yASC) but not old ASCs (oASC).

Figure 5

A) Zymography was performed on lung tissue protein extracts from aged male C57BL/6 mice receiving saline, BLM, BLM+yASC, or BLM+oASC to measure MMP-2 activity. A representative zymogram is shown of two individual mice/group. Data are graphed as the mean ± SEM of n=5–6/group. B) Western blots were performed on lung tissue protein extracts from aged male C57BL/6 mice receiving saline, BLM, BLM+yASC, or BLM+oASC to measure AKT phosphorylation. A representative Western blot is shown of two individual mice/group. Data are graphed as the mean ± SEM of n=5–9/group.* p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.