Table 2. Clinical characteristics of the study cohort.
| Co-infected (C. sinensis/HBV) (n = 51) | Mono HBV infected (HBV) (n = 520) | Mono-C. sinensis infected (n = 53) | Healthy controls (n = 77) | |
|---|---|---|---|---|
| Gender | ||||
| Male | 48 (94%) | 353 (68%) | 43 (81%) | 45 (58%) |
| Female | 3 (6%) | 167 (32%) | 10 (19%) | 32 (42%) |
| Age (years) | ||||
| Mean ± SD | 45.31±1.393 | 36.84±0.4956 | 47.61±1.677 | 41.48±1.548 |
| ≤50 years (n) | 33 (65%) | 311 (60%) | 34 (58%) | 58 (75%) |
| >50 years (n) | 18 (35%) | 209 (40%) | 25 (42%) | 19 (25%) |
| ALT (U/L) | 353.5±89.11abc | 89.33±7.654ac | 38.49±3.979 | 24.14±0.9606 |
| AST (U/L) | 247.9±67.67abc | 66.00±5.256ac | 35.13±2.770 | 24.52±0.9376 |
| TB (μmol/L) | 139.2±21.53abc | 36.96±4.458a | 46.48±13.83 | 12.84±0.7046 |
| HBV DNA copies, log (IU /mL) | 5.495±0. 2229b | 4.952±0.07978 | negative | negative |
Liver function was evaluated by measuring the levels of TB, AST and ALT. C. sinensis infection was diagnosed by counting C. sinensis eggs in stool specimens. Data are expressed as the mean±SD. AST: aspartate aminotransferase; ALT: alanine aminotransferase; HBV: hepatitis B virus; TB: total bilirubin
a Statistically significantly different vs. healthy control subjects
b Statistically significantly different vs. HBV mono-infected patients
c Statistically significantly different vs. C. sinensis mono-infected patients