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. 2016 Jun 27;11(6):e0156961. doi: 10.1371/journal.pone.0156961

Table 2. Characteristics of Studies on Top Four Reported Fiber Types in Database (n = 437).

Total Guar Gum Combination/Mixture Psyllium Dietary Fiber
437 129 (8.7) 111 (7.5) 100 (6.7) 97 (6.5)
Study Design
RCT Crossover 276 (63.2) 97 (75.2) 66 (59.5) 53 (53.0) 60 (61.9)
RCT Parallel 131 (30.0) 22 (17.1) 40 (36.0) 42 (42.0) 27 (27.8)
Other1 30 (6.9) 10 (7.7) 5 (4.5) 5 (5.0) 10 (10.3)
Blinding
Unspecified 241 (55.1) 80 (62.0) 45 (40.5) 39 (39.0) 77 (79.4)
Double-blind 131 (30.0) 36 (27.9) 54 (48.7) 33 (33.0) 8 (8.2)
Single-blind 40 (9.1) 8 (6.2) 10 (9.0) 18 (18.0) 4 (4.1)
Not blinded 24 (5.5) 4 (3.1) 2 (1.8) 10 (10.0) 8 (8.2)
Other2 1 (0.2) 1 (0.8) 0 (0.0) 0 (0.0) 0 (0.0)
Age Category
Adults (20+ y) 331 (75.7) 100 (77.5) 75 (67.6) 76 (76.0) 80 (82.5)
Adults & Adolescents (12–20+ y) 87 (19.9) 22 (17.1) 31 (27.9) 20 (20.0) 14 (14.4)
Other3 19 (4.3) 7 (5.4) 5 (4.5) 4 (4.0) 3 (3.1)
Study Diet
Isocaloric/maintenance 171 (39.1) 35 (27.1) 38 (34.2) 53 (53.0) 45 (46.4)
Acute feeding study 170 (38.9) 73 (56.6) 48 (43.2) 17 (17.0) 32 (33.0)
Unspecified 65 (14.9) 15 (11.6) 13 (11.7) 26 (26.0) 11 (11.3)
Hypocaloric 23 (5.3) 5 (3.9) 9 (8.1) 2 (2.0) 7 (7.2)
Other4 8 (1.8) 1 (0.8) 3 (2.7) 2 (2.0) 2 (2.1)
Level of Feeding Control
Food partially provided (partial metabolic) 183 (41.9) 57 (44.2) 47 (42.3) 61 (61.0) 18 (18.6)
All food provided (metabolic) 200 (45.8) 69 (53.5) 53 (47.8) 25 (25.0) 53 (54.6)
Food recommended 23 (5.3) 0 (0.0) 3 (2.7) 2 (2.0) 18 (18.6)
Dietary guidance with supplement or fiber treatment provided 18 (4.1) 1 (0.8) 5 (4.5) 9 (9.0) 3 (3.1)
Unspecified/other5 13 (3.0) 2 (1.6) 3 (2.7) 3 (3.0) 5 (5.1)
Baseline Health
Healthy 199 (45.5) 60 (46.5) 60 (54.1) 39 (39.0) 40 (41.2)
Metabolically at risk 202 (46.2) 59 (45.7) 45 (40.5) 50 (50.0) 48 (49.5)
GI condition6 17 (3.9) 2 (1.6) 3 (2.7) 9 (9.0) 3 (3.1)
Mixed population 16 (3.7) 8 (6.2) 1 (0.9) 2 (2.0) 5 (5.1)
Other7 3 (0.7) 0 (0.0) 2 (1.8) 0 (0.0) 1 (1.0)

1 includes controlled trials with unspecified randomization, non-randomized trials, combined crossover and randomized controlled trial, and switch-back design

2 time-blinded

3 includes adolescents and studies where age information was not provided

4 includes AHA diet, weight loss diets, and combinations of maintenance or weight loss diets based on individual participant BMI

5 includes mixture of food provided and food partially provided, mixture of food partially provided and food recommended, and not specified

6 includes constipation, diverticular disease, fecal incontinence, loose stools, and hemorrhoids

7 includes recently removed colonic adenomas, or not reported