Skip to main content
. 2016 Jun 6;126(7):2482–2494. doi: 10.1172/JCI85033

Figure 5. Parvalbumin and SST interneurons have varied expression of M1-AChR in the mPFC.

Figure 5

WT mice were perfused, and brains were processed for immunohistology. Representative confocal images of immunofluorescent labeling in the mPFC are shown. (A) Images of PV (green) and M1-AChR (red) in the mPFC are shown. Original magnification, ×40, zoom 2. (B) Images of SST (green) and M1-AChR (red) in the mPFC are shown. Original magnification, ×40, zoom 2. Scale bars: 50 μm. Arrows show interneurons colabeled for specific marker and M1-AChR, while arrowheads show interneurons that do not colabel with M1-AChR. (C and D) Number and proportion of PV and SST interneurons that colocalized with M1-AChR in layers I, II/III, and V of the (C) prelimbic or (D) infralimbic mPFC. Proportions represent the percentage of M1-AChR+ interneurons in each subpopulation and cortical layer indicated.