Figure 2. In vivo expansion and persistence of infused κ.CARTs.

In vivo expansion and persistence of infused κ.CARTs was assessed by qPCR of peripheral blood from patients with NHL or CLL (A) and from patients with MM (B). Data points represent critical post-infusion intervals after the first infusion of κ.CARTs. There was no significant difference in the AUC for additional infusions (Supplemental Figure 2). Dotted lines denote each patient (color key shows universal patient identifier numbers [UPINs]), and the continuous line summarizes the mean expansion and persistence (error bars represent the standard deviation).