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. 2016 Jun 13;126(7):2626–2641. doi: 10.1172/JCI84637

Figure 3. Notch activation shortens lifespan of PB-Pten mice.

Figure 3

(A) Images of PB-Pten and PB-Pten-NICD mice (top) and dissected urogenital organs (bottom). (B) Kaplan-Meier survival curve of PB-Pten and PB-Pten-NICD mice. Log-rank test: P < 1 × 10–4. (C) Transillumination images of urogenital systems and H&E staining of epididymides, vasa deferentia, and seminal vesicles of PB-Pten and PB-Pten-NICD mice. Red bars: 5 mm; black bars: 100 μm.