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. 2016 Jun 21;11:2921–2933. doi: 10.2147/IJN.S107569

Table 1.

Particle size and transparency of different micelle solutions

Formulation Composition (weight%)
Particle size (nm)
Cremophor EL Ethanol Glycerin Mean diameter Transparency
Ethanol 0 system
Z1 0.01 0 2.2
Z2 0.05 0 2.2
Z3 0.5 0 2.2
Z4 1 0 2.2
Z5 3 0 2.2 17.50±0.26
Z6 4 0 2.2 17.73±0.15
Z7 5 0 2.2 17.27±0.31
Ethanol 0.5% system
F1 0.01 0.5 2.2 359.43±6.1 ×
F2 0.05 0.5 2.2 192.13±3.76 ×
F3 0.5 0.5 2.2 213.93±6.97 ×
F4 1 0.5 2.2 14.73±0.21
F5 3 0.5 2.2 17.3±0.1
F6 4 0.5 2.2 17.53±0.38
F7 5 0.5 2.2 17.33±0.29
Ethanol 1% system
O1 0.01 1 2.2 199.77±7.23 ×
O2 0.05 1 2.2 168.1±2.4 ×
O3 0.5 1 2.2 245.17±4.31 ×
O4 1 1 2.2 14.53±0.4
O5 3 1 2.2 17.37±0.25
O6 4 1 2.2 17.53±0.06
O7 5 1 2.2 17.2±0.3

Notes: Z1–Z4 did not form micelle solutions in this study. Transparency was assessed visually. Data expressed as mean ± standard deviation (n=3). “✓” Transparent micelle solution; “×” non-transparent solution; “–” not formed solution.