Table 3.
pH and osmolarity analysis of different micelle formulations
Formulation | pH
|
Osmolarity (mOsm)
|
||||
---|---|---|---|---|---|---|
Initial pH | After 60 days | Increasing ratioa | Initial osmolarity | After 60 days | Increasing ratiob | |
Stored at room temperature over 60 days | ||||||
Z5 | 7.41±0.01 | 7.39±0.02 | 0.997 | 317.4±7.64 | 303.7±4.62 | 0.957 |
Z6 | 7.42±0.02 | 7.38±0.06 | 0.995 | 316.77±12.86 | 299.87±3.26 | 0.947 |
Z7 | 7.43±0.03 | 7.4±0.03 | 0.996 | 311±10.65 | 298.57±3.95 | 0.96 |
F5 | 7.43±0.03 | 7.41±0.03 | 0.997 | 305.5±3.51 | 296.6±13.67 | 0.971 |
F6 | 7.47±0.02 | 7.41±0.02 | 0.992 | 298.30±9.54 | 304.4±5.03 | 1.02 |
F7 | 7.44±0.01 | 7.4±0.01 | 0.995 | 299.63±2.68 | 296.6±10.82 | 0.99 |
O5 | 7.42±0.03 | 7.42±0.05 | 1 | 309.53±12.11 | 301.67±4 | 0.975 |
O6 | 7.46±0.01 | 7.4±0.05 | 0.992 | 311.13±4.3 | 297.47±2.95 | 0.956 |
O7 | 7.45±0.03 | 7.39±0.07 | 0.992 | 306.37±3.46 | 300.3±3.02 | 0.98 |
Stored at 4°C over 60 days | ||||||
Z5 | 7.41±0.01 | 7.4±0.01 | 0.999 | 317.4±7.64 | 309.03±7.8 | 0.974 |
Z6 | 7.42±0.02 | 7.41±0.02 | 0.999 | 316.77±12.86 | 307.17±7.48 | 0.97 |
Z7 | 7.43±0.03 | 7.39±0.09 | 0.995 | 311±10.65 | 304.87±14.2 | 0.98 |
F5 | 7.43±0.03 | 7.41±0.08 | 0.997 | 305.5±3.51 | 297.7±7.57 | 0.974 |
F6 | 7.47±0.02 | 7.37±0.05 | 0.987 | 298.3±9.54 | 300.13±2.99 | 1.006 |
F7 | 7.44±0.01 | 7.41±0.04 | 0.996 | 299.63±2.68 | 303.27±10.05 | 1.012 |
O5 | 7.42±0.03 | 7.39±0.06 | 0.996 | 309.53±12.11 | 302±9.24 | 0.976 |
O6 | 7.46±0.01 | 7.39±0.07 | 0.991 | 311.13±4.3 | 298.27±3.7 | 0.959 |
O7 | 7.45±0.03 | 7.42±0.03 | 0.996 | 306.37±3.46 | 300.03±5.02 | 0.979 |
Notes:
Increasing ratio = pH after 60 days/initial pH;
increasing ratio = osmolarity after 60 days/initial osmolarity. Data expressed as mean ± standard deviation (n=3). Information about the formulation names is shown in Table 1.