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. 2016 Jun 21;11:2921–2933. doi: 10.2147/IJN.S107569

Table 4.

Schirmer tear test scores with cure

Day 1 Day 3 Day 5
Group 1
AS + O7 11.23±1.1 12.13±1.84a 13.16±2.21a
AS + NS 9.85±1.78 7.78±2.16 6.81±3.08
P1 0.084 0.0007 0.0003
Tear-difference value 1.38±1.79 4.35±1.54 6.35±4.49
Group 2
AS + O4 10.76±1.86 11.16±3.12b 11.65±1.58b
AS + NS 9.93±1.59 7.25±3.14 6.75±2.45
P2 0.3497 0.0254 0.0003
Tear-difference value 0.84±1.8 3.91±4.73 4.90±2.96
Group 3
AS + Restasis 11.06±1.5 10.29±2.07 10.4±2.11c
AS + NS 9.81±2.74 7.58±3.44 6.8±1.94
P3 0.2763 0.0767 0.0032
Tear-difference value 1.25±3.55 2.71±3.12 3.6±3.27

Notes:

a

P<0.05 versus AS + NS in group 1 on the same day;

b

P<0.05 versus AS + NS in group 2 on the same day;

c

P<0.05 versus AS + NS in group 3 on the same day. Data expressed as mean ± standard deviation (n=8). All solutions administered at 50 μL.

Abbreviations: AS, atropine sulfate (1% solution); NS, normal saline.