Table 2.

Univariate analysis of factors associated with OS and DFS

	OS			DFS
	P-value	HR	95% CI	P-value	HR	95% CI
Histological grade
Well	0.021	1.000	Ref	0.022	1.000	Ref
Moderately	0.069	1.868	0.953–3.661	0.079	1.829	0.933–3.585
Poorly	0.006	2.432	1.293–4.577	0.006	2.410	1.281–4.535
Size of primary tumor
≤4 cm	<0.001	1.000	Ref	<0.001	1.000	Ref
>4 cm	<0.001	3.622	2.319–5.659	<0.001	3.782	2.416–5.919
Depth of primary tumor invasion
≤1/2	<0.001	1.000	Ref	<0.001	1.000	Ref
>1/2	<0.001	3.067	1.982–4.746	<0.001	3.198	2.065–4.955
Number of metastatic lymph nodes
0	<0.001	1.000	Ref	<0.001	1.000	Ref
1	0.052	2.017	0.994–4.095	0.045	2.062	1.015–4.186
2–5	0.001	2.554	1.474–4.425	0.001	2.510	1.450–4.344
>5	<0.001	10.521	5.476–20.213	<0.001	8.847	4.628–16.913
Metastatic lymph node ratio
<0.2	<0.001	1.000	Ref	<0.001	1.000	Ref
≥0.2	<0.001	4.313	2.668–6.974	<0.001	4.223	2.614–6.820
Stage (FIGO)
IA2	0.002	1.000	Ref	0.001	1.000	Ref
IB1	0.187	1.872	0.746–4.471	0.194	1.810	0.740–4.430
IB2	0.009	3.556	1.365–9.263	0.011	3.467	1.332–9.028
IIA	0.003	3.795	1.578–9.129	0.003	3.834	1.593–9.227
IIB	0.002	4.312	1.686–11.062	0.002	4.495	1.757–11.501
Treatment regimen
Surgery only	0.010	1.000	Ref	0.010	1.000	Ref
Surgery plus postoperative R	0.011	0.502	0.296–0.853	0.020	0.535	0.315–0.908
Surgery plus postoperative C	0.563	1.184	0.668–2.100	0.364	1.304	0.735–2.312
Surgery plus postoperative CRT	0.042	0.491	0.247–0.976	0.045	0.495	0.249–0.984
Radiotherapy
No	0.001	1.000	Ref	0.001	1.000	Ref
Yes	0.001	0.478	0.308–0.741	0.001	0.489	0.315–0.758

Abbreviations: OS, overall survival; DFS, disease-free survival; HR, hazard ratio; Ref, reference; FIGO, International Federation of Gynecology and Obstetrics; R, radiotherapy; C, chemotherapy; CRT, chemoradiotherapy.