Table 2.
Entire results of neurocognitive status comparison between GPi DBS and STN DBS
| Measure | Included study number | SMD, IV, fixed, 95% CI | Test for heterogeneity
|
Test for overall effect
|
||
|---|---|---|---|---|---|---|
| I2 (%) | P-value | Z | P-value | |||
| Verbal fluency | ||||||
| Semantic fluency | 3 | 0.21 (0.03 to 0.40) | 0 | 0.68 | 2.25 | 0.02 |
| Phonemic fluency | 3 | 0.19 (0.00 to 0.38) | 0 | 0.79 | 1.97 | 0.05 |
| Processing speed | ||||||
| Stroop word reading | 3 | 0.33 (0.10 to 0.56) | 41 | 0.16 | 2.83 | 0.005 |
| Stroop color naming | 3 | 0.19 (−0.29 to 0.67) | 42 | 0.15 | 0.78 | 0.44 |
| Trail making test A | 3 | 0.05 (−0.18 to 0.27) | 27 | 0.26 | 0.39 | 0.69 |
| Language | ||||||
| Boston naming test | 3 | 0.11 (−0.05 to 0.27) | 0 | 0.86 | 1.41 | 0.16 |
| Executive function | ||||||
| Trail making test B | 3 | 0.10 (−0.27 to 0.47) | 41 | 0.16 | 0.55 | 0.58 |
| Stroop color–word interference | 3 | 0.14 (−0.09 to 0.37) | 0 | 0.84 | 1.21 | 0.23 |
| Dementia | ||||||
| MDRS | 2 | 0.14 (−0.05 to 0.33) | 0 | 0.95 | 1.44 | 0.15 |
Abbreviations: GPi, globus pallidus interna; STN, subthalamic nucleus; DBS, deep brain stimulation; SMD, standardized mean difference; IV, inverse variance; CI, confidence interval; MDRS, Mattis dementia rating scale.