Table 1.

Experiment based on uniform design and the observed EE and DL results

Run	Factors			Observed results
	X1 (mg/mL)	X2	X3 (mg)	EE (%)	DL (%)
1	12	8	7	73.33	14.00
2	12	16	6	68.97	13.60
3	12	8	5	79.80	12.10
4	16	16	4	75.00	10.14
5	16	8	7	63.40	13.62
6	16	16	6	70.73	11.49
7	20	4	5	86.72	10.38
8	20	12	4	66.19	8.61
9	20	4	7	84.18	17.41
10	24	12	6	69.79	10.42
11	24	4	5	85.22	10.48
12	24	12	4	76.01	7.10

Notes: X₁, the PLGA concentration; X₂, the volume ratio of the aqueous phase to the oil phase; X₃, the AP feeding amount.

Abbreviations: AP, acetylpuerarin; DL, drug loading; EE, encapsulation efficiency; PLGA, poly(lactide-co-glycolide); UD, uniform design.