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Tissue distribution of 10-HCPT in 4T1-bearing mice after an intravenous administration of 10-HCPT injections and 10-HCPT nanocrystals.
Notes: 10-HCPT content changes in plasma (A), heart (B), liver (C), spleen (D), lung (E), kidney (F), brain (G) and tumor (H) after administration of 10-HCPT injections or nanocrystals. The dosage was 8.0 mg/kg, n=6. **P<0.01; ***P<0.001.
Abbreviation: 10-HCPT, 10-hydroxycamptothecin.
