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. 2016 Apr 8;5:e14022. doi: 10.7554/eLife.14022

Appendix 3—figure 9. Simulations of the original example proposed by Turing (Appendix 3—figure 5) started with small random fluctuations around the homogeneous steady state and a large localized concentration of activator at the center of the domain.

Appendix 3—figure 9.

(a) When the localized perturbation has a high magnitude, after an initial dilution of the perturbation patterning dynamics in agreement with the classical interpretation based on the LALI mechanism can be observed: A peak of activator forms first, and a higher amount of inhibitor appears to diffuse into the surrounding areas to inhibit the spreading of the activator. (b) If the magnitude of the localized perturbation is reduced, a simultaneous formation of activator and inhibitor peaks is observed (black arrows). This suggests that LALI is only a phenomenological description of the effect of the large localized perturbation of the activator rather than a bona fide model of the dynamics of real patterning systems.

DOI: http://dx.doi.org/10.7554/eLife.14022.035