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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Lancet Psychiatry. 2016 Apr 14;3(5):472–480. doi: 10.1016/S2215-0366(15)00579-9

Figure 2. Proposed taxonomy of putative biotypes of neural circuit dysfunction for depression and anxiety based on published work.

Figure 2

The proposed phenotype associated with each proposed neural dysfunction is mentioned above each type of dysfunction. aMPFC=anterior medial prefrontal cortex. AG=angular gyrus. PCC=posterior cingulate cortex (includes precuneus). dACC=dorsal anterior cingulate cortex. aI=anterior insula. TP=temporal pole. SLEA=sublenticular extended amygdala. ACC/MPFC=dorsal medial prefrontal cortex (includes dorsal ACC and vMPFC, including ventral—subgenual and pregenual— and rostral ACC). msPFC=medial superior prefrontal cortex. LPFC=lateral prefrontal cortex. aIPL=anterior inferior parietal lobule. MPFC=medial prefrontal cortex. vMPFC=ventromedial prefrontal cortex. OFC=orbitofrontal cortex. ACC=anterior cingulate cortex. DLPF=dorsoateral prefrontal cortex (includes anterior prefrontal cortex and inferior frontal cortex). PCG=precentral gyrus. DPC=dorsal parietal cortex.