Table 2 Patient characteristics of 235 patients treated with controlled stimulation for ART (mean ± SD) and cycle characteristics of 370 controlled stimulation cycles and outcome of 329 ET (mean ± SD). Bold font: p < 0,05, considered as statistically significant.
| Control groupn = 196 | Patients with PCOSn = 39 | p-value | |
|---|---|---|---|
| Age (years) | 34.13 ± 4,13 | 32.739 ± 4.11 | p = 0.055 |
| BMI (kg/m2) | 23.30 ± 4,35 | 25.86 ± 5.70 | p = 0,007 |
| AMH (ng/ml) | 2.71 ± 2,33 | 7.50 ± 4.72 | p < 0,001 |
| Duration of infertility (years) | 4.22 ± 2,83 | 4.33 ± 2.92 | p = 0.825 |
| Primary infertility (%) | 66.8 | 53.8 | p = 0.121 |
| Number of cycles (n) | 305 | 65 | |
| Number of embryotransfers (n) | 270 | 59 | |
| Agonist protocol (%) | 74.1 | 72.3 | p = 0.476 |
| FSH starting dose (IU) | 172.17 ± 67.228 | 131.92 ± 66.366 | p < 0.001 |
| Total FSH dose (IU) | 1 929.16 ± 895., 893 | 1 721.94 ± 812.872 | p = 0.086 |
| Duration of stimulation (days) | 10.40 ± 2.053 | 11.72 ± 2.886 | p < 0.001 |
| Step up (%) | 35.7 | 53.8 | p = 0.025 |
| Dose adjustment (%) | 44.6 | 60.0 | p = 0.025 |
| Max. serum E2 (pg/ml) | 1 641.35 ± 936.13 | 1 672.77 ± 1 100.22 | p = 0.812 |
| No. of follicles ≥ 16 mm (n) | 7.96 ± 4.112 | 9.81 ± 4.253 | p = 0.001 |
| No. of oocytes (n) | 8.41 ± 4.758 | 9.95 ± 5.311 | p = 0.022 |
| Fertilization rate (%) | 0.559 ± 0.298 | 0.608 ± 0.275 | p = 0.356 |
| Ratio embryo transfer/stimulation cycle | 270/30588.5 % | 59/6590.8 % | |
| Biochemical pregnancy rate/ET (%) | 42.2 | 42.4 | p = 0.547 |
| Clinical pregnancy rate/ET (%) | 34.4 | 32.2 | p = 0.434 |
| Moderate or severe OHSS (%) | 15.7 | 16.9 | p = 0.852 |
| Early pregnancy loss (%) | 10.8 | 21.1 | p = 0.191 |