Table 1.
Baseline characteristics: enrolled versus non-enrolled patients
| Enrolled (N = 1525) | Non-enrolled (N = 2054) | P value | |
|---|---|---|---|
| Age (years) | 70.0 ± 10.6 | 70.0 ± 11.0 | 0.97 |
| Age ≥75 years | 570 (37 %) | 776 (38 %) | 0.81 |
| Male gender | 1117 (73 %) | 1553 (76 %) | 0.11 |
| Body mass index | 24.1 ± 3.6 | 23.9 ± 3.6 (2010) | 0.04 |
| Coexisting condition | |||
| Hypertension | 1260 (83 %) | 1574 (77 %) | <0.0001 |
| Diabetes mellitus | 604 (40 %) | 824 (40 %) | 0.76 |
| Insulin-treated diabetes | 119 (7.8 %) | 176 (8.6 %) | 0.41 |
| Treated with oral medication only | 360 (24 %) | 482 (23 %) | 0.92 |
| Treated with diet therapy only | 125 (8.2 %) | 166 (8.1 %) | 0.9 |
| ESRD (eGFR < 30 mL/min/1.73 m2) not on hemodialysis | 35/1521 (2.3 %) | 93/2054 (4.5 %) | 0.0003 |
| Hemodialysis | 56 (3.7 %) | 141 (6.9 %) | <0.0001 |
| Cardiac risk factor | |||
| Current smoker | 315 (21 %) | 430 (21 %) | 0.84 |
| Prior Stroke | 168 (11 %) | 243 (12 %) | 0.45 |
| Heart failure | 101 (6.6 %) | 191 (9.3 %) | 0.004 |
| Peripheral vascular disease | 142 (9.3 %) | 177 (8.6 %) | 0.47 |
| Clinical characteristics | |||
| Clinical presentation | |||
| Stable coronary artery disease | 1040 (68 %) | 1277 (62 %) | 0.0002 |
| Unstable angina | 229 (15 %) | 299 (15 %) | 0.7 |
| Acute myocardial infarction | 256 (17 %) | 478 (23 %) | <0.0001 |
| Target-vessel location | |||
| Left main coronary artery | 17 (1.1 %) | 160 (7.8 %) | <0.0001 |
| Left anterior descending coronary artery | 866 (57 %) | 1108 (54 %) | 0.09 |
| Left circumflex coronary artery | 361 (24 %) | 460 (22 %) | 0.37 |
| Right coronary artery | 405 (27 %) | 614 (30 %) | 0.03 |
| Bypass graft | 4 (0.3 %) | 17 (0.8 %) | 0.02 |
| Complexity of coronary artery disease | |||
| Number of treated lesions per patient | 1.21 ± 0.48 | 1.43 ± 0.74 | <0.0001 |
| Multi-vessel treatment | 130 (8.5 %) | 315 (15 %) | <0.0001 |
| Reasons for non-enrollment | |||
| Physicians’ judgment not to be suitable for the study | NA | 1276 (62 %) | |
| Patients’ refusal for study participation | NA | 292 (14 %) | |
| Others | NA | 486 (24 %) | |
Values are expressed as mean ± SD or number (%)
ESRD end stage renal disease, eGFR estimated glomerular filtration rate