Table 4.
No. of patients with at least one event (cumulative incidence) | P value | ||
---|---|---|---|
STOPDAPT (N = 1525) | RESET (N = 1559) | ||
Primary Endpoint | 42 (2.8 %) | 61 (4.0 %) | 0.06 |
Death | |||
All-cause | 30 (2.0 %) | 25 (1.6 %) | 0.49 |
Cardiac death | 9 (0.6 %) | 13 (0.9 %) | 0.4 |
Cardiovascular death | 10 (0.7 %) | 15 (1.0 %) | 0.33 |
Non-cardiac death | 21 (1.4 %) | 12 (0.8 %) | 0.11 |
Myocardial infarction | 4 (0.3 %) | 18 (1.2 %) | 0.003 |
Stroke | |||
Any | 17 (1.1 %) | 21 (1.4 %) | 0.51 |
Ischemic | 14 (0.9 %) | 15 (1.0 %) | 0.86 |
Hemorrhagic | 4 (0.3 %) | 8 (0.5 %) | 0.24 |
Bleeding | |||
TIMI major | 12 (0.8 %) | 12 (0.8 %) | 0.99 |
TIMI minor/major | 15 (1.0 %) | 20 (1.3 %) | 0.4 |
TIMI minimal/minor/major | 37 (2.5 %) | 38 (2.5 %) | 0.9 |
GUSTO severe | 10 (0.7 %) | 16 (1.0 %) | 0.23 |
GUSTO moderate/severe | 16 (1.1 %) | 19 (1.2 %) | 0.61 |
Definite stent thrombosis | |||
All patients | 0 (0 %) | 4 (0.3 %) | 0.046 |
Acute (0–1 day) | 0 (0 %) | 0 (0 %) | |
Subacute (2–30 days) | 0 (0 %) | 1 (0.06 %) | |
Late (31–365 days) | 0 (0 %) | 3 (0.2 %) | |
Stent thrombosis | |||
Possible | 6 (0.4 %) | 7 (0.5 %) | 0.78 |
Probable | 0 (0 %) | 1 (0.07 %) | 0.32 |
Definite/probable | 0 (0 %) | 5 (0.3 %) | 0.03 |
Definite/probable/possible | 6 (0.4 %) | 12 (0.8 %) | 0.16 |
Death or myocardial infarction | 34 (2.2 %) | 40 (2.6 %) | 0.49 |
Cardiovascular death or myocardial infarction | 14 (0.9 %) | 30 (2.0 %) | 0.02 |
Cardiovascular death, MI or stroke | 31 (2.1 %) | 49 (3.2 %) | 0.045 |
Cardiovascular death, MI, stroke and definite ST | 31 (2.1 %) | 49 (3.2 %) | 0.045 |
Target-lesion revascularization | 30 (2.0 %) | 62 (4.2 %) | 0.0007 |
Target-vessel revascularization | 55 (3.7 %) | 102 (6.9 %) | <0.0001 |
Coronary revascularization | |||
Any | 109 (7.3 %) | 175 (11.8 %) | <0.0001 |
Coronary artery bypass grafting | 3 (0.2 %) | 7 (0.5 %) | 0.2 |
Values are expressed as number (%)
TIMI thrombolysis in myocardial infarction, GUSTO global utilization of streptokinase and tissue plasminogen activator for Occluded coronary arteries, MI myocardial infarction, ST stent thrombosis