Table 1.
Semiquantitative histomorphometric score modified by those of Svensson, Soslowsky, and Cook.
Parameter | Grade 0 | Grade 1 | Grade 2 | Grade 3 |
---|---|---|---|---|
Fiber structure, Svensson and Soslowsky scores | Normal appearance with collagen straight parallel and packed fibers, tangentially oriented with slight waviness | Mild changes with collagen fibers <25% slightly separated with increased waviness | Moderate changes with collagen fibers ≥25% and ≤50% disorganized, separated, and deteriorated | Marked changes with collagen fibers >50% structurally disorganized, and hyalinized |
Cellularity (aspect), Cook scores | Inconspicuous elongated spindle nuclei with no obvious cytoplasm | Increased roundness: nucleus becomes more ovoid to round in shape without conspicuous cytoplasm | Increased roundness and size: the nucleus is round, slightly enlarged, and a small amount of cytoplasm is visible | Nucleus is round and large with abundant cytoplasm and lacuna formation |
Vascularity, Svensson scores | Vessels run inconspicuous coursing parallel to the collagen fiber bundles in the septa | Slight increase in vessels including transverse vessels in the tendon tissue | Moderate increase in vessels within the tendon tissue | Markedly increased vascularity with vessels |
Cartilage formation | No cartilage formation | Isolated hyaline cartilage nodules | Moderate cartilage formation of 25–50% | Extensive cartilage formation, more than 50% of the field involved |