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. 2016 Jun 28;4(12):e12787. doi: 10.14814/phy2.12787

Table 1.

Responses of PPN cells by cell type, and oscillation amplitude and frequency, following exposure to the specific cAMP/PK pathway inhibitor H‐89 or both H‐89 and the specific P/Q‐type channel blocker Aga

Channel type Cell type Osc. Amp. (mV) Osc. Amp. (mV) +H‐89 Osc. Amp. (mV) +H‐89 + Aga Osc. Freq. (Hz) Osc. Freq. (Hz) +H‐89 Osc. Freq. (Hz) +H‐89 + Aga
N + PQ I–0/14 2.47 ± 0.34 1.59 ± 0.29 0.88 ± 0.08 47 ± 7 48 ± 5 56 ± 6
14/25 II–13/14 ↓36% ↓65% ↑2% ↑17%
56% III–1/14 P < 0.05 P < 0.05
P/Q only I–2/4 1.49 ± 0.40 1.85 ± 0.50 0.95 ± 0.18 54 ± 12 38 ± 7 39 ± 6
4/25 II–2/4 NR ↓49% ↓30% ↑2%
16% III–0/4 P < 0.05
N only I–1/7 1.53 ± 0.17 0.98 ± 0.11 1.50 ± 0.23 41 ± 7 38 ± 5 46 ± 8
7/25 II–6/7 ↓35% NR ↓7% ↑18%
28% III–0/7 P < 0.05

Arrows denote percent increase or percent decrease