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Biochemical and biophysical control of perinatal pulmonary circulation which is summarized from our previous in vivo and in vitro studies in ovine fetal and newborn lambs (Bixby et al. 2007; Heymann et al. 1990; Ibe et al. 1998, 2000, 2002, 2005, 2007) and other perinatal reports (Haworth and Reid 1976; Dhanakoti et al. 2000; Montrucchio et al. 2000). Ovine fetal pulmonary hemodynamics favors vasoconstrictors while newborn hemodynamics favors vasodilators.
