Table 1.

Serotonin receptor gene candidate SNPs and the meta-analyses supporting their associations.

Gene	SNP	AKAa	Proxy SNPb	Supporting meta-analysis
HTR1A	rs6295	1019C/G	rs878567	Depression (Kishi et al., 2009, 2013), Bipolar Disorder (Kishi et al., 2011)
HTR1B	rs6296	861G/C	rs6298	ADHD (Gizer et al., 2009)
	rs130058	–161A/T		Substance Abuse (Cao et al., 2013)
	rs11568817	–261T/G		Substance Abuse (Cao et al., 2013)
HTR2A	rs7997012			Anti-depressant response (Niitsu et al., 2013; Lin et al., 2014)
	rs6313	102T>C	rs6311	Anti-depressant response (Kato and Serretti, 2010; Niitsu et al., 2013; Lin et al., 2014); OCD (Taylor, 2013), Schizophrenia (Gu et al., 2013; Gatt et al., 2015), Substance Abuse (Cao et al., 2014), Panic Disorder (Howe et al., 2016)
HTR3B	rs1176744	p.Y129S		Bipolar Disorder (Hammer et al., 2012)

^aAKA = “also known as.”

^bWe use the term “proxy SNP” here refer to SNPs in high LD with the candidate SNP.