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. 2016 Jun 28;10:299. doi: 10.3389/fnins.2016.00299

Table 4.

Top associations (pcorr < 0.10) with DMN components from the 99 SNP HTR1B and HTR2A-wide analysis.

Model parameter DMN component SNP β SE t-value p-value pcorra
SNP × PTSD interactions Right MTG rs977003 −0.00253 0.0006 −4.1046 7.23E-05 0.0282
Right MTG rs7322347 −0.00253 0.0006 −4.0406 9.21E-05 0.0352
Right mPFC rs7997012 0.00193 0.0004 3.9281 0.0001 0.0503
Right mPFC rs7322347 −0.00193 0.0004 −3.8892 0.0001 0.0575
Right mPFC rs1328684 0.00206 0.0005 3.8631 0.0001 0.0623
a

pcorr refers to significance estimate derived from multiple-testing correction across the 11 HTR1B and 88 HTR2A SNPs and eight DMN measures examined in this analysis. Age, sex, and the first two genetic PCs were included as covariates. No SNP main effects were significant. All of the SNPs listed in this table were from HTR2A. mPFC, Medial Prefrontal Cortex; MTG, Middle Temporal Gyrus.