Table 2. The Predictive THEA Score to Estimate the Risk on Developing Overt Autoimmune Hyperthyroidism or Hypothyroidism in the Next 5 Years.
| Variable | Score |
|---|---|
| TSH, mU/L | |
| <0.4 | 2 |
| 0.4-2.0 | 0 |
| 2.1-4.0 | 2 |
| 4.1-5.7 | 4 |
| >5.7 | 6 |
| TPO-Ab, kU/L | |
| <100 | 0 |
| 100-1,000 | 4 |
| 1,001-10,000 | 6 |
| >10,000 | 12 |
| Family members | |
| 2 Members Graves | 1 |
| 2 Members Hashimoto | 3 |
| Maximal score | 21 |
| THEA score, observed/expected event, % | |
| 0-7 Low | 2.7/2.6 |
| 8-10 Medium | 14.6/13.1 |
| 11-15 High | 27.1/32.9 |
| 16-21 Very high | 76.9/59.4 |
Adapted from Strieder et al. [7].
THEA, Thyroid Events Amsterdam; TSH, thyroid-stimulating hormone; TPO-Ab, thyroid peroxidase antibody.