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. 2016 May 13;31(2):311–319. doi: 10.3803/EnM.2016.31.2.311

Table 2. Means for Thyroid Hormone Levels by Select Metabolic Syndrome Components.

Variable No. (%) Thyroid hormones
TSH, mU/L T3, nmol/L T4, nmol/L T3-to-T4 ratio
BMI, kg/m2
 Underweight (<18.5) 219 (2) 2.6±1.3a,* 1.67±0.28a,* 109.7±17.4a,‡ 0.015±0.003a,*
 Normal (18.5-24.9) 8,992 (66) 2.4±1.3a,* 1.71±0.28b,* 108.8±17.9a,‡ 0.016±0.003b,*
 Overweight (25-29.9) 4,042 (30) 2.2±1.2b,* 1.75±0.28c,* 108.0±17.9b,‡ 0.017±0.003c,*
 Obesity (≥30) 243 (2) 2.2±1.2b,* 1.79±0.26d,* 110.9±20.0c,‡ 0.017±0.003c,*
Systolic BP, mm Hg
 <130 10,272 (76) 2.3±1.3 1.71±0.28* 108.3±17.8* 0.016±0.003
 ≥130e 3,224 (24) 2.3±1.3 1.76±0.29* 109.7±18.3* 0.017±0.003
Diastolic BP, mm Hg
 <85 10,756 (80) 2.3±1.3 1.71±0.28* 108.3±17.8* 0.016±0.003
 ≥85e 2,739 (20) 2.3±1.3 1.76±0.29* 109.9±18.5* 0.017±0.003
HDL-C, mg/dL
 Lowf 1,555 (12) 2.5±1.3* 1.68±0.28* 108.8±17.7 0.016±0.003*
 Highg 11,941 (88) 2.3±1.3* 1.73±0.28* 108.6±17.9 0.017±0.003*
Triglycerides, mg/dL
 <150 9,966 (74) 2.3±1.3 1.70±0.28* 108.8±17.9 0.016±0.003*
 ≥150 3,530 (26) 2.4±1.3 1.80±0.28* 108.1±18.1 0.017±0.003*
Fasting glucose, mg/dL
 <100 11,484 (85) 2.4±1.3* 1.72±0.28* 108.6±17.8 0.016±0.003*
 ≥100h 2,012 (15) 2.2±1.2* 1.75±0.29* 108.6±18.6 0.017±0.003*
HbA1c, %
 <5.7 10,636 (79) 2.4±1.3a,‡ 1.72±0.28a,* 108.5±17.8a,† 0.016±0.003a,*
 5.7-6.4 1,992 (15) 2.3±1.3a,b,‡ 1.75±0.29b,* 108.6±17.8a,† 0.017±0.003b,*
 ≥6.5h 868 (6) 2.2±1.3b,‡ 1.73±0.30a,* 110.4±19.6b,† 0.016±0.003a,*

Values are expressed as mean±SD. Thyroid hormone levels of the study population with respect to the cut-off values of metabolic syndrome components were compared using an independent t test or one-way analysis of variance as appropriate for the variable.

TSH, thyroid stimulating hormone; T3, triiodothyronine; T4, thyroxine; BMI, body mass index; BP, blood pressure; HDL-C, high density lipoprotein cholesterol; HbA1c, glycated hemoglobin.

a,b,c,dThe same letters indicate non-significant difference between groups based on Tukey's multiple comparison test; eInclude patients on antihyper-tensive medication regardless of systolic or diastolic BP levels; fHDL-C <40 mg/dL in men or <50 mg/dL in women; gHDL-C ≥40 mg/dL in men or ≥50 mg/dL in women; hInclude patients on antidiabetic medication regardless of fasting glucose or HbA1c levels; *P<0.001; 0.001≤P<0.01; 0.01≤P<0.05.