Table 1. Clinical trials testing cancer stem cell-targeted therapies in lung cancer.

Target	Drug	Mechanism of action	Type cancer	Phase	Clinicaltrials.gov Identifier	Other agents	Est. study completion date
Notch	R04929097	γ-secretase inhibitor	Lung	II	NCT01193868		2015
	OMP-21M18	mAb to DL4	Lung	I	NCT01189968	Carboplatin and pemetrexed	2014
Telomerase	Mythramycin	DNA binding antibiotic	Lung	II	NCT01624090		2018

Note: as listed on clinicaltrials.gov on September 8, 2013.