Table 1.
Plasma concentration in ng/mL of VX-745 obtained at sacrifice 1 h after last dose of study drug administration
VX-745 Dose | Median (Range) | Mean (SD) |
0.5 mg/kg | 12.4 (10.1–25.1) | 13.4 (4.5) |
1.5 mg/kg | 33.6 (14.4–42.7) | 31.4 (8.5) |
4.5 mg/kg | 92.1 (71.5–318) | 126.9 (84) |